Distinguished Scientist Seminar Series featuring Kristine Glunde, PhD – “Metabolic Reprogramming in Breast Cancer Metastasis”

IN PERSON

Distinguished Scientist Seminar Series

Kristine Glunde, PhD
Professor of Radiology, Oncology & Biological Chemistry
Director, Applied Imaging Mass Spectrometry (AIMS)
The Johns Hopkins University School of Medicine

Location: PreClinical Building LA2 and via Zoom: https://georgetown.zoom.us/j/99357306789

Title & Abstract: 

“Metabolic Reprogramming in Breast Cancer Metastasis”

Metabolic reprogramming is a hallmark of cancer, enabling cancer cells to rapidly proliferate, survive in harsh environments, invade, metastasize, and resist treatment. Dr. Glunde’s lab is investigating altered key metabolic pathways in breast cancer, including their specific roles in migration, invasion, and metastasis. An integral part of their methodological approach is matrix-assisted laser desorption/ionization (MALDI) imaging, as it allows us to spatially map a plethora of different biomolecules in tissue sections of primary tumors and corresponding metastases. Dr. Glunde’s presentation will highlight their recent findings on how key enzymes in creatine, lipid, and N-glycan metabolism significantly contribute to aberrant cancer metabolic pathways in primary tumors and metastases.